Abstract
Capillary hemangioblastoma (CH) is a tumor of unknown histogenesis that arises primarily in the posterior cranial fossa, either as a sporadic event or in association with von Hippel-Lindau disease. To date, only 6 examples of a tumor with morphological features of CH arising in the somatic soft tissues have been documented in case reports and small series, and 3 of these tumors were associated with a peripheral nerve. Herein, we report a case of CH arising in the gastrocnemius muscle and not associated with a peripheral nerve in a 53-year-old woman with no clinical stigmata or family history of von Hippel-Lindau disease.
MeSH terms
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Antigens, CD34 / metabolism
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Black People / genetics
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Cerebellar Neoplasms / diagnosis
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Cerebellar Neoplasms / diagnostic imaging
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Cerebellar Neoplasms / genetics
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Cerebellar Neoplasms / pathology*
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Cerebellar Neoplasms / surgery
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Cerebellar Neoplasms / ultrastructure
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Factor XIIIa / metabolism
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Female
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Follow-Up Studies
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Hemangioblastoma / diagnosis
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Hemangioblastoma / diagnostic imaging
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Hemangioblastoma / genetics
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Hemangioblastoma / pathology*
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Hemangioblastoma / surgery
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Hemangioblastoma / ultrastructure
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Humans
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Immunohistochemistry
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Inhibins / metabolism
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Magnetic Resonance Imaging
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Middle Aged
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Muscle, Skeletal / diagnostic imaging
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Muscle, Skeletal / pathology*
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Muscle, Skeletal / surgery
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Muscle, Skeletal / ultrastructure
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Phosphopyruvate Hydratase / metabolism
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Platelet Endothelial Cell Adhesion Molecule-1 / metabolism
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Radiography
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S100 Proteins / metabolism
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Stromal Cells / pathology
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Stromal Cells / ultrastructure
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Time Factors
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Treatment Outcome
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Vimentin / metabolism
Substances
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Antigens, CD34
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Platelet Endothelial Cell Adhesion Molecule-1
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S100 Proteins
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Vimentin
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inhibin-alpha subunit
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Inhibins
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Factor XIIIa
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Phosphopyruvate Hydratase