Assessment of mandibular bone mineral density in patients with type 2 diabetes mellitus

Dentomaxillofac Radiol. 2005 Nov;34(6):327-31. doi: 10.1259/dmfr/52540810.


Objectives: To assess mandibular bone mineral density in patients with type 2 diabetes mellitus using panoramic radiographs.

Methods: Nineteen patients with type 2 diabetes mellitus and 17 control subjects participated in the study. Bone mineral density measurements were performed on the panoramic radiographs with the help of a five-step copper stepwedge phantom, attached to each film cassette, which was calibrated before hand by dual energy X-ray absorptiometry (DXA). The analysis was performed on digitized images by dedicated software (Scion Image). The accuracy of the measurement technique was also evaluated by cross-calibration with a DXA phantom.

Results: Mean mandibular bone mineral density (g cm(-2)) was 1.53+/-0.27 in women and 1.52+/-0.29 in men with type 2 diabetes. In age and gender matched control subjects the values were 1.56+/-0.28 and 1.46+/-0.23 in women and in men, respectively. No statistically significant difference was observed between groups in mandibular bone mineral density.

Conclusions: The present study showed that bone mineral density of the mandible does not seem to be affected in patients with type 2 diabetes mellitus. We also observed that a panoramic radiograph could serve for accurate mandibular bone density determination, when calibrated well with the DXA method.

Publication types

  • Evaluation Study

MeSH terms

  • Absorptiometry, Photon
  • Adult
  • Aged
  • Bone Density*
  • Case-Control Studies
  • Diabetes Mellitus, Type 2 / diagnostic imaging*
  • Diabetes Mellitus, Type 2 / physiopathology
  • Female
  • Humans
  • Male
  • Mandible / chemistry
  • Mandible / diagnostic imaging*
  • Mandible / physiopathology
  • Middle Aged
  • Radiography, Panoramic
  • Regression Analysis
  • Statistics, Nonparametric