Case Reports
doi: 10.1038/4371108a.
Avian flu: isolation of drug-resistant H5N1 virus
Affiliations
- PMID: 16228009
- DOI: 10.1038/4371108a
Item in Clipboard
Case Reports
Avian flu: isolation of drug-resistant H5N1 virus
Nature.
.
Erratum in
- Nature. 2005 Dec 8;438(7069):754
Abstract
The persistence of H5N1 avian influenza viruses in many Asian countries and their ability to cause fatal infections in humans have raised serious concerns about a global flu pandemic. Here we report the isolation of an H5N1 virus from a Vietnamese girl that is resistant to the drug oseltamivir, which is an inhibitor of the viral enzyme neuraminidase and is currently used for protection against and treatment of influenza. Further investigation is necessary to determine the prevalence of oseltamivir-resistant H5N1 viruses among patients treated with this drug.
Similar articles
-
Oseltamivir resistance in influenza A (H5N1) infection.N Engl J Med. 2006 Mar 30;354(13):1423-4; author reply 1423-4. doi: 10.1056/NEJMc060077. N Engl J Med. 2006. PMID: 16571890 No abstract available.
-
Oseltamivir resistance--disabling our influenza defenses.N Engl J Med. 2005 Dec 22;353(25):2633-6. doi: 10.1056/NEJMp058291. N Engl J Med. 2005. PMID: 16371626 No abstract available.
-
Comparison of efficacies of RWJ-270201, zanamivir, and oseltamivir against H5N1, H9N2, and other avian influenza viruses.Antimicrob Agents Chemother. 2001 Oct;45(10):2723-32. doi: 10.1128/AAC.45.10.2723-2732.2001. Antimicrob Agents Chemother. 2001. PMID: 11557461 Free PMC article.
-
Neuraminidase inhibitor susceptibility network position statement: antiviral resistance in influenza A/H5N1 viruses.Antivir Ther. 2005;10(8):873-7. Antivir Ther. 2005. PMID: 16430192 Review.
-
Neuraminidase inhibitors for the treatment and prevention of influenza.Expert Opin Pharmacother. 2002 Feb;3(2):103-12. doi: 10.1517/14656566.3.2.103. Expert Opin Pharmacother. 2002. PMID: 11829724 Review.
Cited by
-
Synthesis of Rupestonic Acid L-Ephedrine Derivatives with Preliminary In vitro Anti-influenza Viral Activity.Curr Pharm Des. 2024;30(18):1398-1403. doi: 10.2174/0113816128282194240329045625. Curr Pharm Des. 2024. PMID: 38623973
-
Impact of the H274Y Substitution on N1, N4, N5, and N8 Neuraminidase Enzymatic Properties and Expression in Reverse Genetic Influenza A Viruses.Viruses. 2024 Mar 1;16(3):388. doi: 10.3390/v16030388. Viruses. 2024. PMID: 38543754 Free PMC article.
-
Activation of Immune and Antiviral Effects by Euglena Extracts: A Review.Foods. 2023 Dec 11;12(24):4438. doi: 10.3390/foods12244438. Foods. 2023. PMID: 38137241 Free PMC article. Review.
-
Diatomic iron nanozyme with lipoxidase-like activity for efficient inactivation of enveloped virus.Nat Commun. 2023 Nov 11;14(1):7312. doi: 10.1038/s41467-023-43176-4. Nat Commun. 2023. PMID: 37951992 Free PMC article.
-
Resistance profiles for the investigational neuraminidase inhibitor AV5080 in influenza A and B viruses.Antiviral Res. 2023 Sep;217:105701. doi: 10.1016/j.antiviral.2023.105701. Epub 2023 Aug 9. Antiviral Res. 2023. PMID: 37567255 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
