Treatment of splenic injury during laparoscopic nephrectomy with BioGlue, a surgical adhesive

Urology. 2005 Oct;66(4):882. doi: 10.1016/j.urology.2005.04.054.


Splenic laceration is a recognized complication of both open and laparoscopic renal surgery. Laparoscopic renal surgery continues to become the new standard of care, and this potentially problematic complication may be encountered during mobilization to gain access to the retroperitoneum. We present 2 cases of splenic injury managed with BioGlue, a new surgical adhesive, during one hand-assisted and one pure laparoscopic nephrectomy. Application of the BioGlue adhesive resulted in satisfactory hemostasis for both injuries without the need for further intervention. These preliminary observations suggest that BioGlue may be a useful addition to the urologic armamentarium to achieve hemostasis in laparoscopic surgery.

Publication types

  • Case Reports

MeSH terms

  • Adhesives*
  • Aged
  • Hemostasis, Surgical / methods*
  • Hemostatic Techniques*
  • Humans
  • Intraoperative Complications / therapy*
  • Laparoscopy*
  • Male
  • Middle Aged
  • Nephrectomy / methods*
  • Proteins*
  • Spleen / injuries*


  • Adhesives
  • Bio-glue
  • Proteins