Bacterial interference for prevention of urinary tract infection: a prospective, randomized, placebo-controlled, double-blind pilot trial

Clin Infect Dis. 2005 Nov 15;41(10):1531-4. doi: 10.1086/497272. Epub 2005 Oct 13.

Abstract

This prospective, randomized, placebo-controlled, double-blind pilot trial examined the efficacy of bacterial interference in preventing urinary tract infection (UTI) in 27 patients with spinal cord injury. Patients whose bladders became colonized with Escherichia coli 83972 were half as likely (P=.01) than noncolonized patients to develop UTI during the subsequent year.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Double-Blind Method
  • Escherichia coli / classification
  • Escherichia coli / metabolism
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Spinal Cord Injuries / complications
  • Urinary Bladder / microbiology
  • Urinary Catheterization / adverse effects
  • Urinary Tract Infections / etiology
  • Urinary Tract Infections / prevention & control*
  • Urinary Tract Infections / urine
  • Urine / microbiology