Changes in health status experienced by women with gestational diabetes and pregnancy-induced hypertensive disorders

J Womens Health (Larchmt). 2005 Oct;14(8):729-36. doi: 10.1089/jwh.2005.14.729.


Objective: To examine changes in health status among women with gestational diabetes mellitus (GDM) and pregnancy-induced hypertension (PIH).

Methods: We examined perceived health status changes from the prepregnancy, as recalled at 12-20 weeks gestation, to the postpartum period in women with GDM (n = 64) vs. unaffected gravidas (n = 1233) and women diagnosed with PIH (n = 148) vs. unaffected gravidas. We used patient survey and medical record data from a prospective cohort study. Health status measures included the Short Form-36 scales for physical function, vitality, and self-rated health and the Center for Epidemiologic Studies-Depression Scale (CES-D). Multivariate logistic regression models controlled for age, parity, race, education, prepregnancy body mass index (BMI) and exercise levels, food insufficiency, and GDM or PIH during a prior pregnancy.

Results: Women with PIH more often reported a significant decline in vitality (odds ratio [OR] 1.51, 95% confidence interval [CI] 1.02-2.23) and self-rated health (OR 2.12, 95% CI 1.19- 3.77) and an increase in depressive symptoms from prepregnancy to postpartum compared with unaffected women (OR 1.84, 95% CI 1.11-3.05). Decline in self-rated health was partially mediated by cesarean birth and preterm delivery. Similar proportions of women with GDM and unaffected women reported declines in health status measures.

Conclusions: Women with PIH, but not GDM, more often experience significant declines in health status from prepregnancy to postpartum than unaffected women.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • California / epidemiology
  • Cohort Studies
  • Confidence Intervals
  • Depression, Postpartum / diagnosis*
  • Depression, Postpartum / etiology
  • Diabetes, Gestational / epidemiology
  • Diabetes, Gestational / physiopathology*
  • Female
  • Health Status*
  • Humans
  • Hypertension / epidemiology
  • Hypertension / physiopathology*
  • Logistic Models
  • Maternal Welfare*
  • Medical Records
  • Odds Ratio
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / epidemiology
  • Pregnancy Complications, Cardiovascular / physiopathology*
  • Pregnancy Outcome
  • Prospective Studies