Segmental cutaneous hemangioma and spinal arteriovenous malformation (Cobb syndrome). Case report and historical perspective

J Neurosurg Spine. 2005 Sep;3(3):249-52. doi: 10.3171/spi.2005.3.3.0249.


The discovery of either a dermatomal cutaneous nevus or a spinal arteriovenous malformation (AVM) should raise the suspicion of Cobb syndrome. The Cobb syndrome is a neurocutaneous syndrome in which there are metameric cutaneous and spinal AVMs. The authors present the case of a patient with acute cervical myelopathy and subtle cutaneous hemangiomas in whom a cervical perimedullary fistula was discovered. They also acknowledge Harvey Cushing's contribution to the recognition of this syndrome.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adolescent
  • Arteriovenous Malformations / pathology*
  • Arteriovenous Malformations / therapy*
  • Embolization, Therapeutic
  • Hemangioma / pathology*
  • Humans
  • Male
  • Neck Pain / etiology
  • Quadriplegia / etiology
  • Syndrome
  • Treatment Outcome