Concomitant chronic inflammatory demyelinating polyneuropathy and myasthenia gravis following cytomegalovirus infection

J Neurol Sci. 2006 Jan 15;240(1-2):103-6. doi: 10.1016/j.jns.2005.08.013. Epub 2005 Oct 19.

Abstract

We describe a patient who concomitantly developed chronic inflammatory demyelinating polyneuropathy (CIDP) and myasthenia gravis (MG) following cytomegalovirus (CMV) infection. Whereas CIDP and MG presumably have different immunopathogeneses, a number of reports presented cases with CIDP and MG, some of which were concomitant cases. Several reports described association between CIDP or MG, and CMV infection, although the association is still a matter of controversy. This is the first report of patients with concomitant CIDP and MG following CMV infection. The association may be coincidental, but the possibility that CMV infection triggered development of both CIDP and MG simultaneously cannot be excluded.

Publication types

  • Case Reports

MeSH terms

  • Cytomegalovirus Infections / complications*
  • Disease Progression
  • Electric Stimulation / methods
  • Female
  • Humans
  • Middle Aged
  • Myasthenia Gravis / etiology*
  • Myasthenia Gravis / virology
  • Neural Conduction / physiology
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / etiology*
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / virology
  • Time Factors