As the source of brewed tea preparations, Camellia sinensis has operated for centuries at the interface of agriculture, politics, and biology. The purpose of this review is to present an inter-disciplinary survey of issues surrounding cultivation, processing, and consumption of the tea plant. Particular attention is given to the biologic effects of tea: first, assessing at the level of human physiology its value as a chemopreventive and chemotherapeutic agent; second, examining effects of production upon local ecosystems, due to resource demands and industrial farming practices. In sum, C. sinensis emerges as a potentially powerful contributor to both public health and economic growth if its role is managed from a prospective, sustainable, and evidence-based vantage.