The JAK2 V617F tyrosine kinase mutation in myelodysplastic syndromes (MDS) developing myelofibrosis indicates the myeloproliferative nature in a subset of MDS patients

Leukemia. 2005 Dec;19(12):2359-60. doi: 10.1038/sj.leu.2403989.
No abstract available

Publication types

  • Letter

MeSH terms

  • Cell Proliferation
  • Humans
  • Janus Kinase 2
  • Mutation, Missense
  • Myelodysplastic Syndromes / genetics*
  • Myelodysplastic Syndromes / pathology*
  • Primary Myelofibrosis
  • Protein-Tyrosine Kinases / genetics*
  • Proto-Oncogene Proteins / genetics*

Substances

  • Proto-Oncogene Proteins
  • Protein-Tyrosine Kinases
  • JAK2 protein, human
  • Janus Kinase 2