Electrophysiological assessment of visual pathway function in infants

Eye (Lond). 1992;6 ( Pt 2):145-53. doi: 10.1038/eye.1992.30.


The flash ERG and VEP have conspicuous immature features during the first 4 months following birth. The most marked maturational changes occur in ERG amplitude and VEP latency. Concurrent recording of the skin ERG and VEP provides information which is very useful in helping to arrive at a diagnosis in the young infant with nystagmus who appears to be blind and has a fundus of normal appearance. ERG and VEP features associated with Leber's Amaurosis, congenital cone dysfunction, albinism, optic nerve hypoplasia and unilateral hemisphere dysfunction are described.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Electroretinography
  • Evoked Potentials, Visual / physiology*
  • Humans
  • Infant
  • Infant, Newborn
  • Retina / physiology*
  • Vision Disorders / diagnosis
  • Vision Disorders / physiopathology
  • Visual Pathways / physiology*