Abstract
Major components of MeOH extracts from the plant roots of Cnidosculus urens purified by cc and tlc and crystallization were lupeol acetate and the previously unreported compounds isoxochitlolone [1] and xochitloldione [2], which were identified through mass, ir, nmr, and uv spectroscopy and X-ray crystallography. In preliminary testing, isoxochitlolone has been found to be active against Escherichia coli and Staphylococcus aureus.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Anti-Bacterial Agents / analysis
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Chromatography, Thin Layer
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Crystallization
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Cyclohexanones / analysis
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Cyclohexanones / isolation & purification*
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Cyclohexanones / pharmacology
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Escherichia coli / drug effects
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Mexico
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Microbial Sensitivity Tests
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Phenols / analysis
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Phenols / isolation & purification*
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Phenols / pharmacology
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Plants, Medicinal / chemistry*
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Staphylococcus aureus / drug effects
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X-Ray Diffraction
Substances
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Anti-Bacterial Agents
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Cyclohexanones
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Phenols
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isoxochitlolone
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xochitloldione