Isolation and identification of xochitloldione and isoxochitlolone from Cnidosculus urens

J Nat Prod. 1992 Feb;55(2):221-4. doi: 10.1021/np50080a011.

Abstract

Major components of MeOH extracts from the plant roots of Cnidosculus urens purified by cc and tlc and crystallization were lupeol acetate and the previously unreported compounds isoxochitlolone [1] and xochitloldione [2], which were identified through mass, ir, nmr, and uv spectroscopy and X-ray crystallography. In preliminary testing, isoxochitlolone has been found to be active against Escherichia coli and Staphylococcus aureus.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anti-Bacterial Agents / analysis
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Chromatography, Thin Layer
  • Crystallization
  • Cyclohexanones / analysis
  • Cyclohexanones / isolation & purification*
  • Cyclohexanones / pharmacology
  • Escherichia coli / drug effects
  • Mexico
  • Microbial Sensitivity Tests
  • Phenols / analysis
  • Phenols / isolation & purification*
  • Phenols / pharmacology
  • Plants, Medicinal / chemistry*
  • Staphylococcus aureus / drug effects
  • X-Ray Diffraction

Substances

  • Anti-Bacterial Agents
  • Cyclohexanones
  • Phenols
  • isoxochitlolone
  • xochitloldione