Glycolipids from sponges. Part 16.(1) discoside, a rare myo-inositol-containing glycolipid from the caribbean sponge Discodermia dissoluta

Lucia Barbieri; Valeria Costantino; Ernesto Fattorusso; Alfonso Mangoni

doi:10.1021/np050241q

Glycolipids from sponges. Part 16.(1) discoside, a rare myo-inositol-containing glycolipid from the caribbean sponge Discodermia dissoluta

J Nat Prod. 2005 Oct;68(10):1527-30. doi: 10.1021/np050241q.

Authors

Lucia Barbieri¹, Valeria Costantino, Ernesto Fattorusso, Alfonso Mangoni

Affiliation

¹ Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli "Federico II", Via D. Montesano 49, 80131 Napoli, Italy.

PMID: 16252919
DOI: 10.1021/np050241q

Abstract

Discoside (1a), a glycolipid composed of 4,6-O-diacylated mannose attached to the 2-hydroxyl group of a myo-inositol unit, was isolated as a mixture of homologues from the marine sponge Discodermia dissoluta. The complete stereostructure of this new glycolipid was solved by interpretation of mass spectrometric and NMR data and CD analysis of degradation products.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Caribbean Region
Glycolipids / chemistry*
Glycolipids / isolation & purification*
Inositol / analogs & derivatives*
Inositol / chemistry*
Inositol / isolation & purification
Marine Biology
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Porifera / chemistry*

Substances

Glycolipids
discoside
Inositol