Classifying wine according to geographical origin via quadrupole-based ICP-mass spectrometry measurements of boron isotope ratios

Anal Bioanal Chem. 2005 Nov;383(6):977-84. doi: 10.1007/s00216-005-0093-7. Epub 2005 Nov 9.


The potential of quadrupole-based ICP-MS as a tool for B-isotopic analysis of wines and its usefulness in provenance determinations were assessed. A precision of 0.1-0.25% RSD (corresponding to a relative standard deviation of the mean of three replicate measurements of 0.06-0.12%) was sufficient to establish small differences in the B isotope ratios in wines from different geographical origins. Each sample measurement was bracketed by measurements of a standard and mass bias drift correction made by interpolation. Sample preparation was kept to a minimum to avoid possible fractionation. Dilution of the wine samples by a factor of 100 with 0.65% HNO3 was found to reduce matrix-induced mass discrimination substantially. Wines from three wine-producing regions, Stellenbosch, Robertson, and Swartland, in the Western Cape Province of South Africa, and wines from specific regions in France (Bergerac) and Italy (Valpolicella) were analyzed by ICP-QMS for their B-isotopic compositions. It was concluded that the 11B/10B ratios can be used to characterize wines from different geographical origins. Average 11B/10B ratios in red wines from South Africa (Stellenbosch), France (Bergerac), and Italy (Valpolicella) were found to differ by between 0.5 and 1.5%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Boron / analysis*
  • France
  • Isotopes / analysis
  • Italy
  • Mass Spectrometry / methods*
  • South Africa
  • Wine / analysis*
  • Wine / classification*


  • Isotopes
  • Boron