Thrombolysis with streptokinase during cardiopulmonary resuscitation: a single center experience and review of the literature

J Thromb Thrombolysis. 2005 Dec;20(3):169-73. doi: 10.1007/s11239-005-3547-z.

Abstract

Objective: To report our experience with use of thrombolysis with streptokinase during cardiopulmonary resuscitation of patients with cardiac arrest due to myocardial infarction.

Design: A case series.

Methods: Thrombolytic therapy (streptokinase) was administered during cardiopulmonary resuscitation of 4 patients with suspected myocardial infarction as the cause of cardiac arrest.

Results: 3 of the 4 patients survived and were discharged from the hospital without any major complications or neurological sequela.

Conclusion: Thrombolysis with streptokinase during cardiopulmonary resuscitation of patients with suspected acute myocardial infarction is associated with reduced mortality and favorable neurological outcome.

MeSH terms

  • Adult
  • Cardiopulmonary Resuscitation*
  • Female
  • Fibrinolytic Agents / therapeutic use*
  • Heart Arrest / drug therapy*
  • Heart Arrest / etiology
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / complications
  • Myocardial Infarction / drug therapy*
  • Streptokinase / therapeutic use*
  • Thrombolytic Therapy*

Substances

  • Fibrinolytic Agents
  • Streptokinase