An evaluation of immediate sheath removal and use of the Angio-Seal vascular closure device in neuroradiological interventions

Neuroradiology. 2006 Jan;48(1):45-9. doi: 10.1007/s00234-005-0013-8. Epub 2005 Oct 28.


We set out to assess the effect of using an arteriotomy closure device in patients at high risk of access site complications. One-hundred nineteen patients with femoral artery access were prospectively included in five centers in France (56 males, 63 females, age range 20-84 years). The neurointerventional procedures were embolization of intracranial aneurysm (71.4%), carotid angioplasty (11.8%), cerebral angioplasty (1.7%), thrombolysis (0.8%), and other procedures (14.3%). Sheaths were removed and the closure device deployed immediately postprocedure. One patient developed a false aneurysm, and one developed a small hematoma. Neither required treatment. Postdevice deployment bleeding was experienced in three patients (2.5%), requiring minimal management. There were no major complications. Three patients died of causes unrelated to the vessel closure. Patient comfort was 2.2 on a scale of 1 (none) to 10 (severe). The results showed that immediate sheath removal followed by use of the closure device is safe in patients undergoing neurointerventional procedures and offers a low level of patient discomfort. In selected patients, early hospital discharge was possible.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brain Diseases / therapy*
  • Catheterization, Peripheral / adverse effects*
  • Catheterization, Peripheral / instrumentation*
  • Female
  • Femoral Artery*
  • France
  • Hemostatic Techniques / adverse effects*
  • Hemostatic Techniques / instrumentation*
  • Humans
  • Male
  • Middle Aged
  • Patient Satisfaction
  • Prospective Studies
  • Punctures / adverse effects
  • Radiography, Interventional
  • Surveys and Questionnaires