Acute lung injury after hematopoietic stem cell transplantation

Clin Chest Med. 2005 Dec;26(4):561-9, vi. doi: 10.1016/j.ccm.2005.06.009.


Hematopoietic stem cell transplantation (HSCT) has emerged as a common therapeutic option for a variety of life-threatening disorders, especially hematologic malignancies. Pulmonary complications are reported in 30% to 60% of all recipients and represent a major cause of mortality. A major proportion of these complications are the direct result of infection. This article addresses early, noninfectious causes of acute lung injury in the HSCT recipient.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Hematologic Neoplasms / surgery
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Respiratory Distress Syndrome / etiology*