The pathogenesis of edema disease in pigs. A review

Vet Microbiol. 1992 Jun 1;31(2-3):221-33. doi: 10.1016/0378-1135(92)90080-d.


Edema disease is known to cause important losses in the period shortly after weaning. Although the disease is known for many decades, intensive studies with bacterial lysates of pathogenic E. coli, followed by biotechnological research the last ten years, has led to a better understanding of its pathogenesis. Especially the impact of the toxin is clearly established. Evidence also exists that adhesion factors play a crucial role in the pathogenesis of edema disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Edema Disease of Swine / etiology*
  • Endotoxins / biosynthesis
  • Endotoxins / genetics
  • Endotoxins / physiology*
  • Escherichia coli / growth & development*
  • Escherichia coli / pathogenicity
  • Swine


  • Endotoxins
  • endotoxin, Escherichia coli