The Chlamydia pneumoniae type III secretion-related lcrH gene clusters are developmentally expressed operons

J Bacteriol. 2005 Nov;187(22):7853-6. doi: 10.1128/JB.187.22.7853-7856.2005.

Abstract

Two chlamydial homologues of the Yersinia lcrH chaperone for type III secretion system structural components are present within separate gene clusters. Quantitative transcriptional analyses demonstrated that each cluster is differentially regulated and expressed as an operon using major sigma factor elements, suggesting the presence of more elaborate developmental regulation mechanisms in chlamydiae.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacterial Proteins / genetics*
  • Biological Transport / genetics*
  • Chlamydophila pneumoniae / genetics*
  • Gene Expression Profiling
  • Gene Expression Regulation, Bacterial*
  • Genes, Bacterial
  • Molecular Chaperones / genetics*
  • Multigene Family
  • Operon
  • RNA, Bacterial / analysis
  • RNA, Messenger / analysis
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sigma Factor

Substances

  • Bacterial Proteins
  • Molecular Chaperones
  • RNA, Bacterial
  • RNA, Messenger
  • Sigma Factor
  • SycD protein, bacteria