Regression of Sweet's syndrome associated with Crohn's disease after anti-Tumour Necrosis Factor therapy

Acta Gastroenterol Belg. 2005 Jul-Sep;68(3):376-9.


The association of inflammatory bowel disease and acute febrile neutrophilic dermatitis (Sweet's syndrome) has infrequently been reported in the literature. We describe the case of a 41-year-old Caucasian woman with ileo- anal Crohn's disease who presented simultaneously an erythema nodosum and a Sweet's syndrome. A dramatic regression of the cutaneous lesions was observed after infliximab treatment, indicating that this therapy might be useful for both Crohn's disease and Sweet's syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Monoclonal / therapeutic use*
  • Crohn Disease / blood
  • Crohn Disease / complications*
  • Dermatologic Agents / therapeutic use*
  • Female
  • Follow-Up Studies
  • Humans
  • Infliximab
  • Sweet Syndrome / blood
  • Sweet Syndrome / complications
  • Sweet Syndrome / drug therapy*
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors*
  • Tumor Necrosis Factor-alpha / metabolism


  • Antibodies, Monoclonal
  • Dermatologic Agents
  • Tumor Necrosis Factor-alpha
  • Infliximab