Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 77 (1-2), 57-89

Regeneration of Descending Axon Tracts After Spinal Cord Injury


Regeneration of Descending Axon Tracts After Spinal Cord Injury

Ronald Deumens et al. Prog Neurobiol.


Axons within the adult mammalian central nervous system do not regenerate spontaneously after injury. Upon injury, the balance between growth promoting and growth inhibitory factors in the central nervous system dramatically changes resulting in the absence of regeneration. Axonal responses to injury vary considerably. In central nervous system regeneration studies, the spinal cord has received a lot of attention because of its relatively easy accessibility and its clinical relevance. The present review discusses the axon-tract-specific requirements for regeneration in the rat. This knowledge is very important for the development and optimalization of therapies to repair the injured spinal cord.

Similar articles

See all similar articles

Cited by 31 PubMed Central articles

See all "Cited by" articles

Publication types

MeSH terms

LinkOut - more resources