New technologies for burn wound closure and healing--review of the literature

Burns. 2005 Dec;31(8):944-56. doi: 10.1016/j.burns.2005.08.023. Epub 2005 Nov 4.


Methods for handling burn wounds have changed in recent decades. Increasingly, aggressive surgical approach with early tangential excision and wound closure is being applied leading to improvement in mortality rates of burn victims. Autografts from uninjured skin remain the mainstay of treatment. Autologous skin graft, however, has limited availability and is associated with additional morbidity and scarring. Severe burn patients invariably lack sufficient adequate skin donor sites requiring alternative methods of skin replacement. The present review summarizes available replacement technologies.

Publication types

  • Review

MeSH terms

  • Burns / therapy*
  • Genetic Therapy / methods
  • Humans
  • Medical Laboratory Science*
  • Skin Transplantation / methods
  • Skin, Artificial
  • Wound Healing*