Patterns of genetic polymorphism at the 10 X-chromosome STR loci in Mongol population

Qingbo Liu; Shengbin Li

doi:10.1016/j.forsciint.2005.04.027

Patterns of genetic polymorphism at the 10 X-chromosome STR loci in Mongol population

Forensic Sci Int. 2006 Apr 20;158(1):76-9. doi: 10.1016/j.forsciint.2005.04.027. Epub 2005 Nov 8.

Authors

Qingbo Liu¹, Shengbin Li

Affiliation

¹ Key Laboratory of Environment and Genes Related to Diseases, Xi'an Jiaotong University, Ministry of Education, Xi'an Shaanxi 710061, China.

PMID: 16280221
DOI: 10.1016/j.forsciint.2005.04.027

Abstract

Genetic diversity at 10 X-chromosome STR loci has been approved and widely used for forensic science field. In this paper, we have studied this genetic diversity in various Mongol ethnic group with geographic backgrounds. Allele frequencies of 10 X-chromosome STR loci, including DXS7133, DXS6799, DXS8378, DXS7423, DXS6804, HPRTB, DXS7424, DXS7132, DXS6789 and DXS101, were obtained from healthy unrelated individuals (53 females and 47 males) of Mongol ethnic group lived in north China. Gene diversity analysis showed that the average heterozygosity was uniformly high (0.687) in the studied population. The coefficient of PIC was 0.99998.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

China
Chromosomes, Human, X*
DNA Fingerprinting / methods
Ethnicity / genetics
Female
Gene Frequency*
Genetics, Population*
Humans
Male
Mongolia / ethnology
Polymerase Chain Reaction
Polymorphism, Genetic*
Tandem Repeat Sequences*