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Case Reports
. 2005 Nov;24(11):1010-1.
doi: 10.1097/01.inf.0000183758.15605.68.

Hypotonic-hyporesponsive Episode in a 7-month-old Infant After Receipt of Multiple Vaccinations

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Case Reports

Hypotonic-hyporesponsive Episode in a 7-month-old Infant After Receipt of Multiple Vaccinations

Paul McPherson et al. Pediatr Infect Dis J. .

Abstract

A 7-month-old boy became difficult to arouse, was limp and had blue extremities 8 hours after immunization with intravenous poliovirus, diphtheria-tetanus toxoids-acellular pertussis, Haemophilus influenzae type b-hepatitis B virus and pneumococcal vaccines. The hypotonic-hyporesponsive episode had resolved by the time the infant was seen in an emergency department 1 hour later. The report describes hypotonic-hyporesponsive episode, encourages reporting of vaccine-associated adverse events and discusses prognosis and implications for subsequent immunization.

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