Abstract
A case is presented of a patient with psoriasis in whom squamous cell carcinoma most likely occurred due to the interaction of various factors (psoralen-ultraviolet A therapy, sun exposure, and suppression of natural killer cell function). Therapy consisted of 1 mg/kg/daily of etretinate (Tegison), which resulted in clearing of psoriatic lesions in one month's time. New carcinomas did not develop and natural killer function improved.
MeSH terms
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Adult
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Carcinoma, Squamous Cell / etiology
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Carcinoma, Squamous Cell / pathology
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Etretinate / therapeutic use
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Humans
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Killer Cells, Natural / immunology*
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Male
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Neoplasms, Multiple Primary / etiology
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Neoplasms, Multiple Primary / pathology
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Neoplasms, Radiation-Induced / etiology*
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Neoplasms, Radiation-Induced / pathology
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Photochemotherapy / adverse effects*
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Psoriasis / drug therapy*
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Psoriasis / immunology
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Skin Neoplasms / etiology*
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Skin Neoplasms / pathology
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Sunlight / adverse effects*