Role of acid/base transporters in the male reproductive tract and potential consequences of their malfunction

Physiology (Bethesda). 2005 Dec:20:417-28. doi: 10.1152/physiol.00036.2005.

Abstract

Acid/base transporters play a key role in establishing an acidic luminal environment for sperm maturation and storage in the male reproductive tract. Impairment of the acidification capacity of the epididymis, via either genetic mutations or exposure to environmental factors, may have profound consequences on male fertility.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acid-Base Equilibrium*
  • Acids / metabolism*
  • Animals
  • Genitalia, Male / metabolism*
  • Humans
  • Infertility, Male / etiology*
  • Male
  • Membrane Transport Proteins / physiology*

Substances

  • Acids
  • Membrane Transport Proteins