Progressive vocal cord dysfunction subsequent to a chlorine gas exposure

J Voice. 2006 Jun;20(2):291-6. doi: 10.1016/j.jvoice.2005.04.003. Epub 2005 Nov 15.


Chlorine gas inhalation, similar to other toxic gas exposures, can impart a variety of effects to the entire airway ranging from mucous membrane irritation to acute respiratory distress syndrome. The extent and location of damage is determined by numerous situational factors such as the duration of exposure, quantity of gas released, environmental factors, and instituted chemical defense measures. Reactive airways dysfunction and nonspecific bronchial hyperresponsiveness are commonly reported as sequelae to chlorine exposure. This article constitutes the first case of a single antecedent chlorine exposure inducing progressive vocal cord dysfunction.

Publication types

  • Case Reports

MeSH terms

  • Administration, Inhalation
  • Chlorine / administration & dosage
  • Chlorine / adverse effects*
  • Disease Progression
  • Dyspnea / chemically induced
  • Humans
  • Male
  • Middle Aged
  • Occupational Diseases / chemically induced*
  • Occupational Exposure / adverse effects*
  • Respiratory Function Tests
  • Vocal Cords / drug effects*
  • Vocal Cords / physiopathology
  • Voice Disorders / chemically induced*


  • Chlorine