Recent progress in the battle between oncolytic viruses and tumours

Nat Rev Cancer. 2005 Dec;5(12):965-76. doi: 10.1038/nrc1750.


In the past 5 years, the field of oncolytic virus research has matured significantly and is moving past the stage of being a laboratory novelty into a new era of preclinical and clinical trials. What have recent anticancer trials of oncolytic viruses taught us about this exciting new line of therapeutics?

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Clinical Trials as Topic
  • Genetic Variation
  • Humans
  • Linkage Disequilibrium
  • Neoplasms / therapy*
  • Neoplasms / virology
  • Oncolytic Virotherapy*
  • Oncolytic Viruses / physiology*
  • Risk Factors