Plastic bronchitis: new insights and a classification scheme

Paediatr Respir Rev. 2005 Dec;6(4):292-300. doi: 10.1016/j.prrv.2005.09.001. Epub 2005 Nov 8.


Plastic bronchitis is a rare disease in which there is the formation of large gelatinous or rigid branching airway casts. The history of the disease is reviewed and a classification system is proposed based on our current understanding. This system classifies plastic bronchitis by clinical disease association and cast histology. A summary of the medical literature is included together with guidelines for treatment. The evidence for these treatment decisions is reviewed.

Publication types

  • Review

MeSH terms

  • Anemia, Sickle Cell / epidemiology
  • Bronchitis / classification*
  • Bronchitis / epidemiology
  • Bronchitis / genetics
  • Bronchitis / pathology
  • Bronchitis / therapy
  • Comorbidity
  • Eosinophils / pathology
  • Genetic Predisposition to Disease
  • Heart Diseases / epidemiology
  • Humans