Efficacy of antiperspirants on feet

Mil Med. 1992 May;157(5):256-9.


Nineteen male soldiers participated in a study of the effectiveness of two antiperspirants (aluminum chlorohydrate and aluminum zirconium tetrachlorohydrex glycine) in reducing foot-sweat accumulation and injuries. Each subject was tested before and after antiperspirant application, with a 1-hour treadmill march at 5.6 km/hour in a warm environment. Both antiperspirants decreased (p less than 0.05) foot-sweat accumulation over 50%. There was also a tendency, although not statistically significant, for subjects to incur fewer blisters with antiperspirant use. However, the antiperspirants also increased (p less than 0.05) the incidence of irritant dermatitis. Nevertheless, these data suggest that the application of antiperspirants to the feet has merit in reducing serious foot injuries (blisters, trench foot) exacerbated by wet feet.

MeSH terms

  • Adult
  • Astringents / pharmacology*
  • Astringents / therapeutic use
  • Blister / prevention & control*
  • Foot Diseases / prevention & control*
  • Humans
  • Male
  • Sweat / drug effects*
  • Treatment Outcome


  • Astringents