Vitamin B12 deficiency in infancy as a cause of developmental regression

Brain Dev. 2005 Dec;27(8):592-4. doi: 10.1016/j.braindev.2005.02.005.

Abstract

Vitamin B12 deficiency can cause serious developmental regression, hypotonia and cerebral atrophy in infants. We report a 6-month-old infant, with insidious developmental regression and brain atrophy showed by CT scan, secondarily to vitamin B12 deficiency. His mother was a strict vegetarian and the patient was exclusively breastfed. The clinical symptoms and the brain CT were normalized after vitamin B12 administration.

Publication types

  • Case Reports

MeSH terms

  • Atrophy
  • Brain / diagnostic imaging
  • Brain / pathology
  • Breast Feeding
  • Developmental Disabilities / etiology*
  • Diet, Vegetarian / adverse effects*
  • Humans
  • Infant
  • Male
  • Muscle Hypotonia / etiology
  • Radiography
  • Vitamin B 12 / therapeutic use
  • Vitamin B 12 Deficiency / complications*
  • Vitamin B 12 Deficiency / drug therapy

Substances

  • Vitamin B 12