Abstract
Enrichment of medium with yeast extract and tryptone increased growth and lactic acid production in batch cultures of Lactobacillus casei ssp. rhamnosus. A reliable kinetic model that explicitly expresses the strong relationship between microbial growth, lactic acid production and medium enrichment is provided and validated using experimental data obtained with six different medium compositions.
Publication types
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Comparative Study
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Evaluation Study
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Research Support, Non-U.S. Gov't
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Validation Study
MeSH terms
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Cell Culture Techniques / methods*
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Cell Proliferation
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Computer Simulation
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Culture Media / metabolism
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Kinetics
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Lactic Acid / biosynthesis*
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Lacticaseibacillus casei / growth & development*
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Lacticaseibacillus casei / metabolism*
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Metabolic Clearance Rate
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Models, Biological*
Substances
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Culture Media
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Lactic Acid