Standardized hypnosis treatment for irritable bowel syndrome: the North Carolina protocol

Int J Clin Exp Hypn. 2006 Jan;54(1):51-64. doi: 10.1080/00207140500322933.


The North Carolina protocol is a seven-session hypnosis-treatment approach for irritable bowel syndrome that is unique in that the entire course of treatment is designed for verbatim delivery. The protocol has been tested in two published research studies and found to benefit more than 80% of patients. This article describes the development, content, and testing of the protocol, and how it is used in clinical practice.

MeSH terms

  • Adaptation, Psychological
  • Autogenic Training
  • Humans
  • Hypnosis*
  • Irritable Bowel Syndrome / diagnosis
  • Irritable Bowel Syndrome / psychology
  • Irritable Bowel Syndrome / therapy*
  • North Carolina
  • Pain Threshold
  • Suggestion
  • Treatment Outcome