Selective site controlled nucleophilic attacks in 5-membered ring phosphate esters: unusual C-O vs. common P-O bond cleavage

Chem Commun (Camb). 2005 Dec 21:(47):5879-81. doi: 10.1039/b512117e. Epub 2005 Oct 31.

Authors

Nissan Ashkenazi¹, Sanjio S Zade, Yoffi Segall, Yishai Karton, Michael Bendikov

Affiliation

¹ Department of Organic Chemistry, IIBR-Israel Institute for Biological Research, Ness-Ziona. nissan.ashkenazi@iibr.gov.il

PMID: 16317461
DOI: 10.1039/b512117e

Abstract

Clean endocyclic C-O bond cleavage has been achieved in the reactions of 5-membered phosphate triesters with various nucleophiles.

Publication types

Research Support, Non-U.S. Gov't