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, 2 (4), 537-48

Can Homeopathic Arsenic Remedy Combat Arsenic Poisoning in Humans Exposed to Groundwater Arsenic Contamination?: A Preliminary Report on First Human Trial

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Can Homeopathic Arsenic Remedy Combat Arsenic Poisoning in Humans Exposed to Groundwater Arsenic Contamination?: A Preliminary Report on First Human Trial

Anisur Rahman Khuda-Bukhsh et al. Evid Based Complement Alternat Med.

Abstract

Groundwater arsenic (As) has affected millions of people globally distributed over 20 countries. In parts of West Bengal (India) and Bangladesh alone, over 100 million people are at risk, but supply of As-free water is grossly inadequate. Attempts to remove As by using orthodox medicines have mostly been unsuccessful. A potentized homeopathic remedy, Arsenicum Album-30, was administered to a group of As affected people and thereafter the As contents in their urine and blood were periodically determined. The activities of various toxicity marker enzymes and compounds in the blood, namely aspartate amino transferase, alanine amino transferase, acid phosphatase, alkaline phosphatase, lipid peroxidation and reduced glutathione, were also periodically monitored up to 3 months. The results are highly encouraging and suggest that the drug can alleviate As poisoning in humans.

Figures

<b>Figure 1</b>
Figure 1
Arsenic (As) content in urine of verum fed subjects vs. placebo fed axes for 11 consecutive days. *P < 0.05, **P < 0.01.
<b>Figure 2</b>
Figure 2
(a) Statistical significance test done between BD and 7D, and between successive fixation intervals, namely, between 7D and 15D, 15D and 30D, and so on; *P < 0.05, **P < 0.01, ***P < 0.001. (b) Statistical significance test done between BD and 1M, and between successive fixation intervals; *P < 0.05, **P < 0.01, ***P < 0.001.
<b>Figure 3</b>
Figure 3
Activities of different biomarkers in blood of verum fed subjects (a) AST (b) ALT (c) AcP (d) AlkP (e) LPO (f) GSH.
<b>Figure 4</b>
Figure 4
(ad) Typical skin symptom on palms (upper row) and soles (lower row) of a victim before (left) and 2 months (right) after administration of Arsenicum Album-30.

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References

    1. Chowdhury UK, Rahman MM, Mondal BK, Paul K, Lodh D, Biswas BK, et al. Groundwater arsenic contamination and human suffering in West Bengal, India and Bangladesh. Environ Sci. 2001;8:393–415.
    1. WHO. WHO Guidelines for Drinking Water Quality. 2nd edition. Vol. 2. Geneva: WHO; 1996. pp. 940–9.
    1. United States Environment Protection Agency. 2001.
    1. Guha Mazumder DN, Das Gupta J, Santra A, Pal A, Ghosh A, Sarkar S, et al. Non-cancer effects of chronic arsenicosis with special reference to liver damage. In: Abernathy CO, Calderon RL, Chappell WR, editors. Asenic: Exposure and Health Effects. London: Chapman & Hall; 1997. pp. 112–23.
    1. Ratnaike RN. Acute and chronic arsenic toxicity. Postgrad Med J. 2003;79:391–6. - PMC - PubMed

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