[Effect of inspiratory muscle training on muscle strength and quality of life in patients with chronic airflow limitation: a randomized controlled trial]

Arch Bronconeumol. 2005 Nov;41(11):601-6. doi: 10.1016/s1579-2129(06)60293-0.
[Article in Spanish]


Objective: Chronic airflow limitation (CAL) is a significant cause of illness and death. Inspiratory muscle training has been described as a technique for managing CAL. The aim of the present study was to evaluate the effectiveness of inspiratory muscle training on improving physiological and functional variables.

Patients and methods: Randomized controlled trial in which 35 patients with CAL were assigned to receive either an experimental (n=17) or control (n=18) intervention. The experimental intervention consisted of 2 months of inspiratory muscle training using a device that administered a resistive load of 40% of maximal static inspiratory mouth pressure (PImax). Inspiratory muscle strength, exercise tolerance, respiratory function, and quality of life were assessed.

Results: Significant improvement in inspiratory muscle strength was observed in the experimental training group (P=.02). All patients improved over time in both groups (P<.001). PImax increased by 8.9 cm H2O per month of training. Likewise, the health-related quality of life scores improved by 0.56 points.

Conclusion: Use of a threshold loading device is effective for strengthening inspiratory muscles as measured by PImax after the first month of training in patients with CAL. The long-term effectiveness of such training and its impact on quality of life should be studied in a larger number of patients.

Publication types

  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Breathing Exercises*
  • Chronic Disease
  • Female
  • Humans
  • Lung Diseases, Obstructive / physiopathology*
  • Lung Diseases, Obstructive / therapy*
  • Male
  • Middle Aged
  • Muscle, Skeletal / physiopathology*
  • Quality of Life*