A pediatric patient with recurrent pseudotumor cerebri and vitamin B12 deficiency

Pediatr Hematol Oncol. Jan-Feb 2006;23(1):39-43. doi: 10.1080/08880010500313322.


Pseudotumor cerebri is a syndrome of increased intracranial pressure, normal cerebrospinal fluid values, and a normal cerebral ventricles on brain imaging studies. A patient with a diagnosis of pseudotumor cerebri was admitted to the authors' hospital twice within a 2.5-year interval and treated with vitamin B12 (vit-B12). At the second admission she also presented with a cerebral venous thrombosis that might have been explained by vit-B12 deficiency, homocysteinemia, and an increased level of lipoprotein-a.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Female
  • Humans
  • Hyperhomocysteinemia
  • Intracranial Thrombosis / etiology
  • Lipoprotein(a)
  • Pseudotumor Cerebri / etiology*
  • Recurrence
  • Remission Induction
  • Venous Thrombosis / etiology
  • Vitamin B 12 / therapeutic use
  • Vitamin B 12 Deficiency / complications*
  • Vitamin B 12 Deficiency / drug therapy


  • Lipoprotein(a)
  • Vitamin B 12