Y-chromosomal STR haplotypes in a Northeast Italian population sample using 17plex loci PCR assay

Int J Legal Med. 2006 Jan;120(1):56-9. doi: 10.1007/s00414-005-0054-x. Epub 2005 Nov 19.


One hundred fifty-five unrelated, autochthonous healthy males from Northeast Italy were typed for the 17 Y-chromosome short tandem repeat (STR) (Y-STR) loci DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385, DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4, DYS437, DYS438, DYS448 using the AmpFLSTR Yfiler polymerase chain reaction amplification kit. A total of 153 different haplotypes were observed, and among these, 151 were unique, while 2 were found two times. The overall haplotype diversity was 0.9997. Furthermore, 50 father-son pairs, previously confirmed by autosomal STR analysis, were typed using the same set of 17 Y-STR loci, and, among 850 allele transfers, three mutation events were identified, giving an average mutation rate of 3.53 x 10(-3) per locus per generation (95% confidence interval 0.73-1.03).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosomes, Human, Y*
  • DNA Fingerprinting
  • Genetic Variation
  • Genetics, Population*
  • Haplotypes*
  • Humans
  • Italy
  • Male
  • Polymerase Chain Reaction
  • Tandem Repeat Sequences*