Objective: To provide a modern method for extraction and separation total flavonoids in Epimedium koreanum.
Method: Using high pressure technology extracts total flavonoids in E. koreanum, and comparing with counter-current extraction with reflux. The total flavonoids contents is determined by UV-VIS.
Result: The extraction efficiency is 9.67% and taking 5 min by high pressure method, using reflux, is 6.14% and 4 h respectively.
Conclusion: The method of high pressure is high efficiency and saving time, which have extensive application in the extraction of Traditional Chinese Medicine.