Background: Botulinum toxins have been proven effective for reducing facial lines. There are two commercial types of botulinum toxin type A available in many countries but no published comparison studies.
Objective: To compare the efficacy and tolerability of Botox Cosmetic and Dysport 50 U in the treatment of glabellar lines (using 20 U of Botox Cosmetic, which is the dose approved by the US Food and Drug Administration for the treatment of glabellar lines, and 50 U of Dysport, which has been reported to be the optimal dose for this formulation).
Study design: Parallel-group double-blind pilot study. Evaluation by observing physician, photographic, and patient evaluations.
Conclusion: Botox 20 U provided better and more prolonged efficacy than Dysport 50 U in the treatment of glabellar lines.