Di-myo-inositol-1,1'-phosphate: a new inositol phosphate isolated from Pyrococcus woesei

FEBS Lett. 1992 Jul 20;306(2-3):239-42. doi: 10.1016/0014-5793(92)81008-a.


A new inositol derivative could be isolated from the Archaeum Pyrococcus woesei and identified as di-myo-inositol-1,1'-phosphate by 1H, 31P NMR spectroscopy, mass spectrometry and thin layer chromatography. In P. woesei, this inositol phosphate represents the dominant counterion of K+ which ranges from 500 to 600 mM. The role of the potassium salt of di-myo-inositol-1,1'-phosphate as thermostabilizer is discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Archaea / chemistry*
  • Archaea / metabolism
  • Chromatography, Thin Layer
  • Enzyme Stability
  • Glyceraldehyde-3-Phosphate Dehydrogenases / metabolism
  • Inositol Phosphates / isolation & purification*
  • Inositol Phosphates / metabolism
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Potassium / metabolism
  • Temperature


  • Inositol Phosphates
  • di-myo-inositol-1,1'-phosphate
  • Glyceraldehyde-3-Phosphate Dehydrogenases
  • Potassium