Inactivation of the central thalamus delays self-timed saccades

Nat Neurosci. 2006 Jan;9(1):20-2. doi: 10.1038/nn1617. Epub 2005 Dec 11.

Abstract

The central thalamus transmits corollary discharge signals for eye movement control, but its role in eye movement generation remains uncertain. Inactivation of the paralaminar part of the ventrolateral thalamus delayed the initiation of contraversive saccades, particularly during a new memory-guided saccade task that required self-triggering of the movement. The results suggest that signals through the thalamus regulate the timing of self-initiated saccades.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Basal Ganglia / cytology
  • Basal Ganglia / physiology
  • Cerebral Cortex / cytology
  • Cerebral Cortex / physiology
  • Fixation, Ocular
  • Haplorhini
  • Memory / physiology
  • Photic Stimulation
  • Saccades / physiology*
  • Thalamus / physiology*
  • Ventral Thalamic Nuclei / physiology