Is hospitalization after TIA cost-effective on the basis of treatment with tPA?

Neurology. 2005 Dec 13;65(11):1799-801. doi: 10.1212/01.wnl.0000187067.93321.fa.

Abstract

A 24-hour hospitalization for TIA could be cost-effective simply by increasing the likelihood that patients will receive tissue plasminogen activator if a stroke occurs. The authors performed a cost-utility analysis of 24-hour hospitalization for patients diagnosed with recent TIA. The overall cost-effectiveness ratio was 55,044 dollars per quality-adjusted life-year, a value considered borderline cost-effective. For patients with higher risk of stroke, admission was cost-effective.

MeSH terms

  • Academic Medical Centers / economics
  • Academic Medical Centers / statistics & numerical data
  • Cost-Benefit Analysis
  • Decision Trees
  • Emergency Service, Hospital / economics
  • Emergency Service, Hospital / statistics & numerical data
  • Fibrinolytic Agents / economics
  • Fibrinolytic Agents / therapeutic use*
  • Hospitalization / economics*
  • Hospitalization / statistics & numerical data
  • Humans
  • Ischemic Attack, Transient / drug therapy*
  • Ischemic Attack, Transient / economics*
  • Markov Chains
  • Models, Statistical
  • Quality-Adjusted Life Years
  • Registries
  • Risk Factors
  • Stroke / prevention & control*
  • Thrombolytic Therapy / economics*
  • Thrombolytic Therapy / standards
  • Tissue Plasminogen Activator / economics
  • Tissue Plasminogen Activator / therapeutic use*

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator