Transcoronary chemical ablation of ventricular tachycardia in chronic chagasic myocarditis

J Am Coll Cardiol. 1992 Aug;20(2):480-2. doi: 10.1016/0735-1097(92)90121-3.


Objective: A case of incessant ventricular tachycardia in a patient with Chagas' disease that was successfully terminated by chemical ablation is reported.

Background: Chagas' disease is a common medical problem in South America. Ventricular tachyarrhythmias, atrioventricular conduction disturbances, congestive heart failure and sudden cardiac death are important manifestations of this disease.

Methods: Selective catheterization of the coronary artery supplying the arrhythmogenic area was performed by using a conventional angioplasty system and the arrhythmogenic area was ablated by injection of 96% sterile ethanol.

Results: Ethanol (96%) injection initially in a lateral branch of the left circumflex artery and 2 days later in the proximal segment of the artery resulted in termination of ventricular tachycardia. Two weeks after ablation, programmed ventricular stimulation failed to induce ventricular tachycardia.

Conclusion: Transcoronary chemical ablation should be considered in selected cases of Chagas' disease with incessant ventricular tachycardia.

Publication types

  • Case Reports

MeSH terms

  • Angioplasty, Balloon, Coronary
  • Chagas Cardiomyopathy / complications*
  • Electrocardiography
  • Ethanol / administration & dosage
  • Ethanol / therapeutic use*
  • Humans
  • Injections, Intra-Arterial
  • Male
  • Middle Aged
  • Myocarditis / parasitology
  • Tachycardia / parasitology
  • Tachycardia / therapy*


  • Ethanol