Our study examined whether perception of novel emotions, as with perception of novel objects, elicits a cardiac orientation reaction. Using a habituation-dishabituation paradigm, data from 11 adult subjects showed that orientation to both novel emotions and novel objects elicited a heart-rate deceleration. Results suggest that the orientation reaction may be an integral part of perception of emotion. Perception of emotions, therefore, is a complex, multistep process that includes an early orientation reaction.