Long term protection after hepatitis B vaccination

Bosn J Basic Med Sci. 2005 Aug;5(3):50-3.


A survey of persistence of anti-HBs after hepatitis B vaccination has shown that five years after vaccination on a sample of 152 persons, or 82.53%, stands at >10 IU/I. Long term immunogenicity of vaccinated children remained at 88.89%, health workers 79.41% and drug addicts 64.28%. The results of these studies in Bosnia and Herzegovina show the high level of protection hepatitis B vaccine against HBV infection. Vaccination against viral hepatitis B results in immunologic memory response among the vaccinated, and even after a decrease of anti-HB level following the third vaccine dose inoculation, a booster dose is not needed. Immunity remains steady and a booster dose is not recommended.

MeSH terms

  • Adult
  • Bosnia and Herzegovina
  • Child
  • Health Personnel
  • Hepatitis B Antibodies / blood*
  • Hepatitis B Vaccines / immunology*
  • Humans
  • Immunization, Secondary
  • Immunologic Memory
  • Needs Assessment
  • Substance-Related Disorders / blood
  • Time Factors


  • Hepatitis B Antibodies
  • Hepatitis B Vaccines