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Review
. 2005 Dec;73(9-10):435-7.
doi: 10.1111/j.1432-0436.2005.00049.x.

How Is the Mouse Germ-Cell Lineage Established?

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Review

How Is the Mouse Germ-Cell Lineage Established?

Anne McLaren et al. Differentiation. .

Abstract

Six cells have been detected in the early mouse embryo that express the transcriptional repressor Blimp1--as also do all the 40 or so cells that constitute the founder germ cell pool a day later. Are these half-dozen cells the ancestors of the entire mouse germ cell lineage?

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