Factors determining patient choice of device for GH therapy

Horm Res. 2006;65(1):18-22. doi: 10.1159/000090375. Epub 2005 Dec 16.


Aim: To assess the factors determining patient choice of GH device, and whether offering free patient choice improves compliance with GH therapy.

Methods: A prospective cross-sectional study performed on patients offered free choice of GH device in a regional growth clinic. In a subgroup having home delivery, GH compliance was assessed using ampoule counts.

Results: 125 patients (74 (59%) male), median (range) 9.30 (1.0-18.3) years were commenced on GH from January 2001 to March 2004, and offered free choice of device. 68 (54%) chose a needled device, and 57 (46%) needle-free. There was no statistical difference in age, sex or diagnostic category between the two groups. Light blue devices were more likely to be chosen by males (p=0.056). Questionnaires giving reasons for choosing a device were available in 40, and a further 50 gave reasons for both choosing a specific device and not choosing others. Other than choice of needled/needle-free device, the factor most likely to determine choice was 'ease of use'. Only 6 (4.8%) subsequently changed device, and compliance remained high but unchanged at approximately 90%.

Conclusions: There are no specific features which determine what GH device a patient will choose. For those units offering free patient choice, a wide range of different devices should be made available.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Choice Behavior
  • Cohort Studies
  • Female
  • Hormone Replacement Therapy / methods*
  • Human Growth Hormone / administration & dosage*
  • Humans
  • Infant
  • Injections, Subcutaneous
  • Male
  • Patient Compliance
  • Prospective Studies


  • Human Growth Hormone