HIV vaccine design: insights from live attenuated SIV vaccines

Nat Immunol. 2006 Jan;7(1):19-23. doi: 10.1038/ni1296.


The International AIDS Vaccine Initiative has established a consortium to elucidate mechanisms of protection conferred by live attenuated simian immunodeficiency virus vaccines in monkeys. Here, the strategies defining key components of the protective immune response elicited by these vaccines are discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • AIDS Vaccines*
  • Acquired Immunodeficiency Syndrome / prevention & control*
  • Animals
  • Haplorhini
  • Humans
  • Simian Acquired Immunodeficiency Syndrome / prevention & control*
  • Simian Immunodeficiency Virus / immunology*
  • Vaccines, Attenuated


  • AIDS Vaccines
  • Vaccines, Attenuated