Perinatal cerebrovascular disease in the neonate. Parenchymal ischemic lesions in term and preterm infants

Pediatr Clin North Am. 1992 Aug;39(4):621-50. doi: 10.1016/s0031-3955(16)38368-7.


Acute cerebrovascular injury in term and preterm infants is a cause of significant morbidity. Treatment efforts in the past have focused on attempts to prevent such injury by interceding during labor in term infants and improving neonatal care in preterm infants. Epidemiologic studies suggest that these strategies have had little impact. A new strategy--drug treatment of acute ischemic brain injury--is on the horizon. The recognition and prognostication in ischemic neonatal brain injury takes on a new importance in this light.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Brain Ischemia / complications
  • Brain Ischemia / diagnosis*
  • Cerebral Hemorrhage / complications
  • Cerebral Hemorrhage / diagnosis*
  • Cerebral Infarction / complications
  • Cerebral Infarction / diagnosis*
  • Cerebral Palsy / etiology
  • Cerebrovascular Disorders / complications
  • Cerebrovascular Disorders / diagnosis*
  • Electroencephalography
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Male
  • Prognosis